Biochemistry, Biophysics, and Structural Biology

Biochemistry, Biophysics, and Structural Biology

genome replication and maintenance •  transcription • RNA splicing • protein synthesis and folding • protein sorting •  protein structure and design •  macromolecular machines • enzymology • metalloproteins • metabolism • molecular modeling • signal transduction • drug design • glycobiology

Phillip A. Sharp
Faculty Spotlight

Phillip A. Sharp

Institute Professor and Professor of Biology; Member, Koch Institute for Integrative Cancer Research

Phillip A. Sharp studies many aspects of gene expression in mammalian cells, including transcription, the roles of non-coding RNAs, and RNA splicing. 

Building a platform to image membrane proteins

Human-human and protein-protein interactions.

Whitehead Institute team resolves structure of master growth regulator

Understanding genetic circuits and genome organization

The chemist and the poet

A summer at the MSRP-Bio reveals connections between proteins, people, and passions

Forging a new understanding of metal-containing proteins

Multi “-omics” approach uncovers the riches of traditional global medicine