Education
- PhD, 1993, Harvard University
- BA, 1982, Biology, Goshen College
Research Summary
We study microRNAs and other small RNAs that specify the destruction and/or translational repression of mRNAs. We also study mRNAs, focusing on their untranslated regions and poly(A) tails, and how these regions recruit and mediate regulatory phenomena.Awards
- National Academy of Sciences, Member, 2011
- Howard Hughes Medical Institute, HHMI Investigator, 2005
- National Academy of Sciences Award in Molecular Biology, 2005
- AAAS Newcomb Cleveland Prize, 2002
Key Publications
- The molecular basis of coupling between poly(A)-tail length and translational efficiency. Xiang, K, Bartel, DP. 2021. Elife 10, .
doi: 10.7554/eLife.66493PMID:34213414 - The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation. Shi, CY, Kingston, ER, Kleaveland, B, Lin, DH, Stubna, MW, Bartel, DP. 2020. Science 370, .
doi: 10.1126/science.abc9359PMID:33184237 - The biochemical basis of microRNA targeting efficacy. McGeary, SE, Lin, KS, Shi, CY, Pham, TM, Bisaria, N, Kelley, GM, Bartel, DP. 2019. Science 366, .
doi: 10.1126/science.aav1741PMID:31806698 - Excised linear introns regulate growth in yeast. Morgan, JT, Fink, GR, Bartel, DP. 2019. Nature 565, 606-611.
doi: 10.1038/s41586-018-0828-1PMID:30651636 - A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain. Kleaveland, B, Shi, CY, Stefano, J, Bartel, DP. 2018. Cell 174, 350-362.e17.
doi: 10.1016/j.cell.2018.05.022PMID:29887379
Recent Publications
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