Biochemistry, Biophysics, and Structural Biology

Biochemistry, Biophysics, and Structural Biology

genome replication and maintenance •  transcription • RNA splicing • protein synthesis and folding • protein sorting •  protein structure and design •  macromolecular machines • enzymology • metalloproteins • metabolism • molecular modeling • signal transduction • drug design • glycobiology

Michael B. Yaffe
Faculty Spotlight

Michael B. Yaffe

Director, MIT Center for Precision Cancer Medicine; David H. Koch Professor in Science; Professor of Biological Engineering; Intramural Faculty, Koch Institute

Michael B. Yaffe studies the chain of reactions that controls a cell’s response to stress, cell injury, and DNA damage.

CHARMed collaboration creates a potent therapy candidate for fatal prion diseases

She’s fighting to stop the brain disease that killed her mother before it gets her

New technique reveals how gene transcription is coordinated in cells

“Rosetta Stone” of cell signaling could expedite precision cancer medicine

Taking RNAi from interesting science to impactful new treatments

News brief: Davis Lab

De-tail-ing RNA regulation in eggs and early embryos

How signaling proteins get to the mitochondrial surface