Biochemistry, Biophysics, and Structural Biology

Biochemistry, Biophysics, and Structural Biology

genome replication and maintenance •  transcription • RNA splicing • protein synthesis and folding • protein sorting •  protein structure and design •  macromolecular machines • enzymology • metalloproteins • metabolism • molecular modeling • signal transduction • drug design • glycobiology

Christopher Burge
Faculty Spotlight

Christopher Burge

CSB Program Director; Uncas (1923) and Helen Whitaker Professor; Extramural Member of KIICR; Associate Member of the Broad Institute

Christopher Burge applies a combination of experimental and computational approaches to understand the regulatory codes underlying pre-mRNA splicing and other types of post-transcriptional gene regulation.

Alternate proteins from the same gene contribute differently to health and rare disease

A new way to understand and predict gene splicing

A more precise way to edit the genome

Can bacteria be used to clean up oil spills?

Locally produced proteins help mitochondria function

Mapping cells in time and space: a new tool reveals a detailed history of tumor growth

Putting liver cells in context: new method combines imaging and sequencing to study gene function in living tissue

MIT Down syndrome researchers work on ways to ensure a healthy lifespan