Angelika Amon examines cell growth and division, and how errors in this process contribute to cancer and aging.
David Bartel studies molecular pathways that regulate eukaryotic gene expression by affecting the stability or translation of mRNAs.
Iain Cheeseman analyzes the process by which cells duplicate, focusing on the molecular machinery that segregates the chromosomes.
Gerald R. Fink investigates how fungal pathogens invade the body, evade the immune system, and establish an infection.
Mary Gehring researches epigenetic mechanisms of gene regulation in plants.
Alan Grossman studies mechanisms and regulation of DNA replication, gene expression, and horizontal gene transfer in bacteria.
Leonard P. Guarente looks at mammal, mouse, and human brains to understand the genetic underpinning of aging and age-related diseases like Alzheimer’s.
Michael T. Hemann uses mouse models to combat cancers resistant to chemotherapy.
Nancy Hopkins worked on the genetics of mouse RNA tumor viruses; on the genetics of early vertebrate development using zebrafish; and on the fish as a cancer model.
H. Robert Horvitz analyzes the roles of genes in animal development and behavior, gaining insight into human disease.
David Housman studies the biological underpinnings of diseases like Huntington’s, cancer, and cardiovascular disease.
Tyler Jacks is interested in the genetic events contributing to the development of cancer, and his group has created a series of mouse strains engineered to carry mutations in genes known to be involved in human cancers.
Chris A. Kaiser analyzes protein folding and trafficking in cells.
Dennis Kim considers the relationship between animals and their microbial environment — specifically, how bacteria influence the behavior and physiology of the simple animal host C. elegans.
Eric S. Lander is interested in every aspect of the human genome and its application to medicine.
Associate Dept. Head
Michael T. Laub explores how bacterial cells process information and regulate their own growth and proliferation, as well as how these information-processing capabilities have evolved.
Troy Littleton is interested in how neuronal connections form and function, and how neurological disease disrupts synaptic communication.
Terry Orr-Weaver probed the incredibly complex and coordinated process of development from egg to fertilized embryo and ultimately adult.
David C. Page examines the genetic differences between males and females — and how these play out in disease, development, and evolution.
Mary-Lou Pardue studied fruit fly chromosomes to better understand chromosome replication, cell division, and related cellular structures.
Uttam RajBhandary's interests include interactions between RNAs and proteins, focusing on gene expression and gene regulation.
Associate Dept. Head
Peter Reddien works to unravel one of the greatest mysteries in biology — how organisms regenerate missing body parts.
Anthony J. Sinskey explores the principles of metabolic engineering in both bacteria and plants.
Graham C. Walker studies DNA repair, mutagenesis, and cellular responses to DNA damage, as well as the symbiotic relationship between legumes and nitrogen-fixing bacteria.
Jing-Ke Weng studies metabolic evolution in plants and explores the remarkable plant chemodiversity for new commodity chemicals and medicines.