Mary Gehring

Mary Gehring

Associate Professor of Biology; Core Member, Whitehead Institute; Graduate Officer

Mary Gehring researches epigenetic mechanisms of gene regulation in plants.

617-324-0343

Phone

WI-561B

Office

Beverly Dobson

Assistant

617-258-5214

Assistant Phone

Education

  • PhD, 2005, University of California, Berkeley
  • BA, 1998, Biology, Williams College

Research Summary

We focus on plant epigenetics — that is, the heritable information that influences cellular function but is not encoded in the DNA sequence itself. We use genetic, genomic and molecular biology approaches to study the fidelity of epigenetic inheritance and the dynamics of epigenomic reprogramming during reproduction, primarily in the model plant Arabidopsis thaliana. More specifically, we investigate the interplay among repetitive sequences, DNA methylation and chromatin structure in these dynamic processes.

Awards

  • Rosalind Franklin Young Investigator Award, 2013
  • Pew Scholar in the Biomedical Sciences, 2011

Recent Publications

  1. RNA Pol IV induces antagonistic parent-of-origin effects on Arabidopsis endosperm. Satyaki, PRV, Gehring, M. 2022. PLoS Biol 20, e3001602.
    doi: 10.1371/journal.pbio.3001602PMID:35389984
  2. Somatic DNA demethylation generates tissue-specific methylation states and impacts flowering time. Williams, BP, Bechen, LL, Pohlmann, DA, Gehring, M. 2022. Plant Cell 34, 1189-1206.
    doi: 10.1093/plcell/koab319PMID:34954804
  3. Maternal-filial transfer structures in endosperm: A nexus of nutritional dynamics and seed development. Povilus, RA, Gehring, M. 2022. Curr Opin Plant Biol 65, 102121.
    doi: 10.1016/j.pbi.2021.102121PMID:34801784
  4. Editorial overview: Multifaceted dynamics and countless shades of green chromatin. Gehring, M, Roudier, F. 2021. Curr Opin Plant Biol 61, 102079.
    doi: 10.1016/j.pbi.2021.102079PMID:34158157
  5. Transcriptional and imprinting complexity in Arabidopsis seeds at single-nucleus resolution. Picard, CL, Povilus, RA, Williams, BP, Gehring, M. 2021. Nat Plants 7, 730-738.
    doi: 10.1038/s41477-021-00922-0PMID:34059805
  6. Principles of Epigenetic Homeostasis Shared Between Flowering Plants and Mammals. Williams, BP, Gehring, M. 2020. Trends Genet 36, 751-763.
    doi: 10.1016/j.tig.2020.06.019PMID:32711945
  7. Water lily (Nymphaea thermarum) genome reveals variable genomic signatures of ancient vascular cambium losses. Povilus, RA, DaCosta, JM, Grassa, C, Satyaki, PRV, Moeglein, M, Jaenisch, J, Xi, Z, Mathews, S, Gehring, M, Davis, CC et al.. 2020. Proc Natl Acad Sci U S A 117, 8649-8656.
    doi: 10.1073/pnas.1922873117PMID:32234787
  8. Identification and Comparison of Imprinted Genes Across Plant Species. Picard, CL, Gehring, M. 2020. Methods Mol Biol 2093, 173-201.
    doi: 10.1007/978-1-0716-0179-2_13PMID:32088897
  9. Paternally Acting Canonical RNA-Directed DNA Methylation Pathway Genes Sensitize Arabidopsis Endosperm to Paternal Genome Dosage. Satyaki, PRV, Gehring, M. 2019. Plant Cell 31, 1563-1578.
    doi: 10.1105/tpc.19.00047PMID:31064867
  10. Epigenetic dynamics during flowering plant reproduction: evidence for reprogramming? Gehring, M. 2019. New Phytol 224, 91-96.
    doi: 10.1111/nph.15856PMID:31002174
More Publications

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Photo credit: Gretchen Ertl/Whitehead Institute