Cancer Biology

Cancer Biology

cancer gene discovery • tumorigenesis • cancer therapy and resistance • oncogenes • tumor suppressor genes • cancer models • growth control and cell proliferation • metastasis • cell proliferation • cell death • cell-cell and cell-matrix interactions • microenvironment •DNA repair and replication • transcription • chromosome stability • metabolism • immunology and cancer • immunotherapy • cancer stem cells

Matthew G. Jones
Faculty Spotlight

Matthew G. Jones

Howard S. (1953) and Linda B. Stern Career Development Professor; Core Member, Koch Institute; Core Member, IMES

Matthew Jones integrates computational and technological advances to decode the molecular processes underlying spatiotemporal tumor evolution, with a focus on genomic instability and extrachromosomal DNA.

Lung cancers can use two different mechanisms to evade KRAS-inhibiting drugs

Cells use a little-known molecule to protect themselves from iron overload

Enzymes that assemble into droplets can speed up cellular reactions

3 Questions with new faculty member Matthew G. Jones: Building predictive models to characterize tumor progression

Studying the genetic basis of disease to explore fundamental biological questions

High-fat diets make liver cells more likely to become cancerous

A cysteine-rich diet may promote regeneration of the intestinal lining, study suggests

A more precise way to edit the genome