Human Disease

Human Disease

developmental disorders • cancer • atherosclerosis and heart disease • neuromuscular diseases • disease genes • genetic pathways of disease • etiology of disease • disease models • assay development • genomics • gene-function-pathology relationships

Jacqueline Lees
Faculty Spotlight

Jacqueline Lees

Virginia and D.K. Ludwig Professor for Cancer Research; Associate Director, Koch Institute

Jacqueline Lees develops mouse and zebrafish models, identifying the molecular pathways leading to tumor formation.

Cellular traffic congestion in chronic diseases suggests new therapeutic targets

A blueprint for better cancer immunotherapies

Bat cells possess a unique antiviral mechanism, preventing the SARS-CoV-2 virus from taking control

Establishing boundaries of the genetic kind

Brain cell types are affected differently by Rett Syndrome mutation

Whitehead Institute researchers uncover a new clue toward understanding the molecular basis of Parkinson’s disease

Study reveals the benefits and downside of fasting

New approach enables a closer look at brain cell organelle