Experiments and mathematical model uncover the mechanisms behind wrinkles in cell nuclei

By studying the changing geometry of cell nuclei in fruit flies, scientists have gained a better understanding of the dynamics that shape the part of our cells that carries our DNA.

November 3, 2023
Award honors Elly Nedivi’s research on cortical plasticity

The Krieg Cortical Kudos Discoverer Award recognizes Nedivi’s ongoing work to understand molecular and cellular mechanisms that enable the brain to adapt to experience

David Orenstein | The Picower Institute for Learning and Memory
November 29, 2023

https://news.mit.edu/2023/award-honors-elly-nedivis-research-cortical-plasticity-1129

https://picower.mit.edu/news/award-honors-elly-nedivis-research-cortical-plasticity

CLAMP complex helps parasites enter human cells

Apicomplexan parasites are responsible for several serious and prevalent diseases, including malaria & toxoplasmosis. New work from the Lourido Lab identifies the CLAMP protein complex, which plays a key role in helping apicomplexan parasites invade new cells.

Greta Friar | Whitehead Institute
October 27, 2023
Gene-Wei Li among the Pew Charitable Trusts’ 2023 class of Innovation Fund investigators

The Pew Charitable Trusts’ 2023 class of Innovation Fund investigators—12 accomplished scientists with expertise in cancer biology, neuroscience, immunology, and more—are pairing up to explore challenges in human health and medicine.

October 24, 2023
Machine learning helps predict drugs’ favorite subcellular haunts

Small molecule drugs, such as those used for cancer treatment, tend to concentrate in specific regions of the cell, and can bind to things besides their intended target. These collective, weak interactions may detain a significant percentage of drug molecules. New research from the Young lab trained a machine learning model to predict where a drug will concentrate based on its chemical features, which may be relevant to understanding many cellular processes and to the design of safe and effective drugs.

September 27, 2023
Considering biological puzzles, one line of code at a time
Lillian Eden | Department of Biology
September 22, 2023