The immune system consists of diverse cell types which collaborate to eliminate infections by a large number of pathogens. This elaborate collaboration involves macrophage, B lymphocytes and T lymphocytes. Macrophages provide a first line of defense by engulfing, digesting, and presenting peptides derived from pathogens to the lymphocytes. B and T cells which are capable of recognizing specific antigens become stimulated to divide and respond to the pathogen. The B cells respond by producing antibodies and the T cells respond by controlling the immune response and killing infected cells. The molecular mechanisms involved in the specificity of the response and in the control of the cellular collaboration are highly complex and interesting, and are the focus of multiple studies in our department.
Faculty with research programs in immunology: