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For more than 40 students from across the globe, the summer was filled with days in the lab experiencing cutting-edge scientific research which culminated in a bustling poster session in August.

Lillian Eden | Department of Biology

September 8, 2023

For 45 undergraduate students from institutions across the US, the summer was filled with days in the lab experiencing cutting-edge scientific research. 

The Bernard S. and Sophie G. Gould MIT Summer research program in Biology (BSG-MSRP Bio) provides undergraduates the chance to work full-time in labs and see behind the curtain of the science—and life—they could have if they decided to pursue graduate studies in scientific research. 

The program is offered in collaboration with MIT’s Department of Brain & Cognitive Sciences (BCS) and the Center for Brains, Minds, and Machines (CBMM), with students working in labs affiliated with the Biology Department, BCS, CBMM, the Department of Chemistry, and the Whitehead Institute. 

The students’ work culminated in a bustling poster session at the beginning of August, hosted by the Picower Institute for Learning and Memory. 

“As always, the poster session was a lively and inspiring event, as students presented results that they sometimes obtained in a rush just days before,” says MIT Biology Department Head Amy Keating. “It was a challenge to see all the posters I wanted to, with people standing several rows deep around the speakers, eager to learn about the new science.”

The purpose of the MSRP-Bio program is to provide an intensive research experience to students who do not have access to cutting-edge research facilities at their home institutions– and to introduce them to MIT. The program offers professional development by bringing in faculty as guest speakers throughout the ten weeks of the program and provides resources like campus housing, stipends, mentoring, and trips around Massachusetts.

Since its inception, MSRP-Bio has left a mark both on the students and on the MIT community. For example, Associate Professor of Biology Joey Davis’ connection to the MSRP-Bio program threads through his career as a researcher.

The MSRP-Bio program launched in 2003, two years before Davis began as a graduate student at MIT. Some students in his graduate student cohort—some who are now his colleagues, including Associate Professor of Biology Eliezer Calo and Assistant Professor of Biology Francisco Sanchez-Rivera were among the initial participants of the MSRP-Bio program. Davis’ first graduate student attended the program, and so did three of his current graduate students. Two students who worked in his lab last summer as part of the program are also returning to pursue PhDs in the Department of Biology this fall. 

“The MSRP students get to hang out with current graduate students and get a sense of the people that you can form lifelong relationships with,” Davis says. “What does it look like to be a scientist? What would my peers be like? It’s a pretty unique opportunity.” 

Davis credits Senior Lecturer Mandana Sassanfar, who spearheads many outreach activities, for her expansive work identifying students who would thrive at MIT and giving them research experiences that aren’t available at their home institutions. 

“It’s hard to identify folks that haven’t had these opportunities before, even though they are so, so capable,” Davis says. “It’s incredible what Mandana has been able to do.”

Since the program began, hundreds of students have participated. The majority went on to enroll in PhD or MD/PhD programs at MIT and other highly-ranked graduate programs nationwide. Almost two dozen are now faculty at various institutions across the U.S. 

For some attendees, the poster session was a blast from the past. Chidera Okeke said her time in the lab of Professor of Biology Adam Martin as an MSRP-Bio student and Gould Fellow was what convinced her to apply to the PhD program. Okeke, a Fisk University alumna, is now a second-year graduate student at MIT in the lab of Class of 1922 Career Development Professor and Whitehead Institute Core Member Olivia Corradin.

“It was the only program I saw that really mirrored grad school and the day-to-day of what it would look like as a PhD student—lab meetings and extracurricular activities,” she says. “I also found out a lot about the application process. People were very transparent about it, and everyone was just genuinely nice.”

She noted, however, that 2021—the year she was a summer student—was the last year of physical posters. Students, since then, have displayed their posters on large TV screens with iPads that allow them to navigate their posters, and the posters include time reminders for when a session is drawing to a close.  

“I honestly prefer the e-poster because I could zoom in,” says MSRP-Bio student Fareeda Abu-Juam, a College of Wooster undergraduate and novice computational biologist who worked in Davis’ lab this summer. She squeezed extra images onto her poster and used the zooming capabilities to better display them for people asking questions.

Because the attendees at the poster session come from different research backgrounds, Abu-Juam says it was an excellent opportunity to answer questions she hadn’t considered before. 

“It’s great that so many people came out to support undergraduates. It’s nice to be in a place where they’re supporting us like that,” said Christina “CJ” Volpe, a student in the lab of Howard S. and Linda B. Stern Career Development Professor and Intramural Faculty at the Koch Institute Stefani Spranger. “I’ve never been at an institution where they’re doing cutting-edge research. Investigating something that has never been done before. It was an amazing experience. I don’t know how I’m going to go back to my home institution now.”

Cyrille Teforlack, an undergraduate from Bethune Cookman University who has been working on flatworm eye regeneration in the lab of Professor of Biology and Core Member and Associate Director of the Whitehead Institute Peter Reddien, says he’s had plenty of practice for the poster session. Between discussing their research informally with fellow 2023 MSRP-Bio students and presenting in lab meetings throughout the summer, MSRP-Bio students have many opportunities to build confidence in discussing their work.

“I’ve gotten really good feedback from people,” he says. “The questions they asked made me think about different questions to think about for my own project.”

Some students also had the opportunity to see what the work was like for newer faculty still in the process of setting up their labs—a helpful thing for those considering academia. MSRP-Bio student Nina Greeley spent the summer in new Whitehead Institute Fellow Lindsey Backman’s lab. Backman, who opened her lab at the Whitehead Institute to study the proteins of anaerobic bacteria in the human microbiome just last year, also participated in the MSRP-Bio program. 

As for what advice Greeley would give to students doing poster sessions for the first time, Greeley had this to say: “People want to know why your work is relevant. Keep it simple. Explain what you did, the result, and how you think the lab will go in future directions.”

In a visit to MIT, the educator and author led a lively and inspiring Q&A with students.

Lillian Eden | Department of Biology

August 9, 2023

A group of more than 50 individuals recently had the pleasure of sitting down for an informal chat at MIT with distinguished educator, author, and mathematician Freeman Hrabowski. The group was predominantly composed of MIT Summer Research Program in Biology (MSRP-Bio) students and alumni and current students from the Meyerhoff Scholars Program and the University of Maryland, Baltimore County.

Hrabowski is widely credited for transforming UMBC into a world-renowned, innovative institution while serving as its president from 1992 to 2022. The educator also ushered in a generation of Black students to earn PhDs in science and engineering, co-founding the Meyerhoff Scholars Program at UMBC. Founded in 1988, the program has become a national model for increasing diversity in STEM. Hrabowski was also a member of the President’s Advisory Commission on Educational Excellence for African Americans during the Obama administration.

Hrabowski began by quoting poet William Carlos Williams: “It is difficult to get the news from poems yet men die miserable every day for lack of what is found there,” and leading a call-and-response recitation of the poem “Dreams,” by Langston Hughes, as well as a mantra encouraging students to use their words, actions, and habits to shape their character and their destiny. Afterward, the students asked Hrabowski about his life and experiences.

“The audience of high-achieving students asked terrific, insightful questions reflecting their contemplation of their own paths,” says Department of Biology head Amy Keating. “When students spoke up, Hrabowski engaged with them, and their ideas and perspectives were welcomed and respected. By the end of his time with them, almost everyone had their hand up and wanted to contribute to the lively discussion.”

Tobias Coombs, a Meyerhoff Scholars program alumnus and current graduate student in the Spranger Lab, says the event was an example of “classic Freeman Hrabowski:” Hrabowski injected the crowd with excitement and energy. Coombs also remarked that Hrabowski, named by Time as one of the world’s most influential people in 2012, acknowledged to the group that he’s shy, something Hrabowski is still pushing himself to overcome.

“He makes a point of being this down-to-earth person that you feel you can talk to about real issues and have real conversations with,” Coombs says. “He genuinely wants to motivate you to think science and math are cool.”

Before taking questions from the students in attendance, Hrabowski posed one to them: What do you think it takes to be successful in research in STEM? Among the responses were passion, curiosity, and a supportive community. After each response, Hrabowski encouraged a round of applause for each student brave enough to stand and give an answer because “everybody needs support.”

“The way that you think about yourselves, the language that you use, the way that you interact with each other, and the values that you hold, will be so important. You become like the things that you love,” Hrabowski says.

For his lifetime of accomplishments increasing diversity in STEM, the Howard Hughes Medical Institute recently announced a new program named after Hrabowski. The HHMI Freeman Hrabowski Scholars were selected for their potential to become leaders in their research fields and to foster diverse and inclusive lab environments. The inaugural class of 31 scholars includes MIT biology faculty members Seychelle Vos, the Robert A. Swanson Career Development Professor of Life Sciences, and Hernandez Moura Silva, an assistant professor and Ragon Institute of MGH, MIT and Harvard core member, as well as MIT biology and Cheeseman lab alumna Kara McKinley PhD ’16.

Vos and Moura Silva were among the faculty attending the event, and both say Hrabowski was an inspiring guest to have on campus.

“Dr. Hrabowski’s smile, energy, and words are a true force of nature,” Hernandez says. “His words of wisdom showed us that we can all make the impossible possible by bringing a positive attitude to build a strong, supportive, and diverse community. It was such an honor to have him here.”

Biology department undergraduate officer Adam Martin says he noticed the pride in Hrabowski’s eyes when Hrabowski discussed what his trainees and faculty in his programs have accomplished. Biology department graduate officer Mary Gehring said his visit made her remember why she wanted to be a professor: “to help others follow their passions to their full potential.”

Hrabowski reflected on many topics, including the recent Supreme Court ruling on affirmative action. He pointed out that this was not the first time the Supreme Court had ruled on a racially conscious initiative, namely the 1995 decision that a UMBC scholarship program was unconstitutional. To continue the Meyerhoff Scholars Program, which was affected by the Supreme Court decision at the time, Hrabowski worked with Maryland’s attorney general, found language and methods to encourage broad participation of diverse individuals, and focused on what the program was trying to achieve.

“My message to everyone was ‘where there’s a will, there’s a way.’ If the institution wants to continue to build diversity and broader participation, we can do it,” he says. “What we’re working to achieve in the Meyerhoff program and in the Freeman Hrabowski Scholars program is to have everybody included.”

Hrabowski also offered advice on more everyday challenges: good students, himself included, can focus too much, forgetting to make time for other important aspects of their lives. He has learned to make time for tai chi, acupuncture, and getting his steps in; he encouraged the students similarly to take time for themselves outside work or school.

“When you can have fun and laugh, you’re a much better person. You can be a better thinker if you take care of yourself overall,” he says. “It’s the healthy person who can be most effective.”

As for being intimidated or nervous to talk to a superior, Hrabowski had the room roaring with laughter at his advice: “Just remember they go to the bathroom, too.”

Keating noted that Hrabowski engaged with the audience with energy, compassion, and humor.

She also observed, “No one can hide in Dr. Hrabowski’s classroom.”

“He put students front and center in his presentation, and his emphasis on the joys and importance of learning, knowledge, and achievement inspired us all to go back to the lab and classroom and be our best selves,” Keating says. “He acknowledged that paths in STEM demand much of us, and he encouraged students to have the discipline needed to stay the course while also taking care of themselves.”

Faculty members were recently granted tenure in the departments of Biology, Brain and Cognitive Sciences, Chemistry, EAPS, and Physics.

School of Science

August 8, 2023

In 2022, nine MIT faculty were granted tenure in the School of Science:

Gloria Choi examines the interaction of the immune system with the brain and the effects of that interaction on neurodevelopment, behavior, and mood. She also studies how social behaviors are regulated according to sensory stimuli, context, internal state, and physiological status, and how these factors modulate neural circuit function via a combinatorial code of classic neuromodulators and immune-derived cytokines. Choi joined the Department of Brain and Cognitive Sciences after a postdoc at Columbia University. She received her bachelor’s degree from the University of California at Berkeley, and her PhD from Caltech. Choi is also an investigator in The Picower Institute for Learning and Memory.

Nikta Fakhri develops experimental tools and conceptual frameworks to uncover laws governing fluctuations, order, and self-organization in active systems. Such frameworks provide powerful insight into dynamics of nonequilibrium living systems across scales, from the emergence of thermodynamic arrow of time to spatiotemporal organization of signaling protein patterns and discovery of odd elasticity. Fakhri joined the Department of Physics in 2015 following a postdoc at University of Göttingen. She completed her undergraduate degree at Sharif University of Technology and her PhD at Rice University.

Geobiologist Greg Fournier uses a combination of molecular phylogeny insights and geologic records to study major events in planetary history, with the hope of furthering our understanding of the co-evolution of life and environment. Recently, his team developed a new technique to analyze multiple gene evolutionary histories and estimated that photosynthesis evolved between 3.4 and 2.9 billion years ago. Fournier joined the Department of Earth, Atmospheric and Planetary Sciences in 2014 after working as a postdoc at the University of Connecticut and as a NASA Postdoctoral Program Fellow in MIT’s Department of Civil and Environmental Engineering. He earned his BA from Dartmouth College in 2001 and his PhD in genetics and genomics from the University of Connecticut in 2009.

Daniel Harlow researches black holes and cosmology, viewed through the lens of quantum gravity and quantum field theory. His work generates new insights into quantum information, quantum field theory, and gravity. Harlow joined the Department of Physics in 2017 following postdocs at Princeton University and Harvard University. He obtained a BA in physics and mathematics from Columbia University in 2006 and a PhD in physics from Stanford University in 2012. He is also a researcher in the Center for Theoretical Physics.

A biophysicist, Gene-Wei Li studies how bacteria optimize the levels of proteins they produce at both mechanistic and systems levels. His lab focuses on design principles of transcription, translation, and RNA maturation. Li joined the Department of Biology in 2015 after completing a postdoc at the University of California at San Francisco. He earned an BS in physics from National Tsinghua University in 2004 and a PhD in physics from Harvard University in 2010.

Michael McDonald focuses on the evolution of galaxies and clusters of galaxies, and the role that environment plays in dictating this evolution. This research involves the discovery and study of the most distant assemblies of galaxies alongside analyses of the complex interplay between gas, galaxies, and black holes in the closest, most massive systems. McDonald joined the Department of Physics and the Kavli Institute for Astrophysics and Space Research in 2015 after three years as a Hubble Fellow, also at MIT. He obtained his BS and MS degrees in physics at Queen’s University, and his PhD in astronomy at the University of Maryland in College Park.

Gabriela Schlau-Cohen combines tools from chemistry, optics, biology, and microscopy to develop new approaches to probe dynamics. Her group focuses on dynamics in membrane proteins, particularly photosynthetic light-harvesting systems that are of interest for sustainable energy applications. Following a postdoc at Stanford University, Schlau-Cohen joined the Department of Chemistry faculty in 2015. She earned a bachelor’s degree in chemical physics from Brown University in 2003 followed by a PhD in chemistry at the University of California at Berkeley.

Phiala Shanahan’s research interests are focused around theoretical nuclear and particle physics. In particular, she works to understand the structure and interactions of hadrons and nuclei from the fundamental degrees of freedom encoded in the Standard Model of particle physics. After a postdoc at MIT and a joint position as an assistant professor at the College of William and Mary and senior staff scientist at the Thomas Jefferson National Accelerator Facility, Shanahan returned to the Department of Physics as faculty in 2018. She obtained her BS from the University of Adelaide in 2012 and her PhD, also from the University of Adelaide, in 2015.

Omer Yilmaz explores the impact of dietary interventions on stem cells, the immune system, and cancer within the intestine. By better understanding how intestinal stem cells adapt to diverse diets, his group hopes to identify and develop new strategies that prevent and reduce the growth of cancers involving the intestinal tract. Yilmaz joined the Department of Biology in 2014 and is now also a member of Koch Institute for Integrative Cancer Research. After receiving his BS from the University of Michigan in 1999 and his PhD and MD from University of Michigan Medical School in 2008, he was a resident in anatomic pathology at Massachusetts General Hospital and Harvard Medical School until 2013.

In 2023, five MIT faculty were granted tenure in the School of Science:

Physicist Riccardo Comin explores the novel phases of matter that can be found in electronic solids with strong interactions, also known as quantum materials. His group employs a combination of synthesis, scattering, and spectroscopy to obtain a comprehensive picture of these emergent phenomena, including superconductivity, (anti)ferromagnetism, spin-density-waves, charge order, ferroelectricity, and orbital order. Comin joined the Department of Physics in 2016 after postdoctoral work at the University of Toronto. He completed his undergraduate studies at the Universita’ degli Studi di Trieste in Italy, where he also obtained a MS in physics in 2009. Later, he pursued doctoral studies at the University of British Columbia, Canada, earning a PhD in 2013.

Netta Engelhardt researches the dynamics of black holes in quantum gravity and uses holography to study the interplay between gravity and quantum information. Her primary focus is on the black hole information paradox, that black holes seem to be destroying information that, according to quantum physics, cannot be destroyed. Engelhardt was a postdoc at Princeton University and a member of the Princeton Gravity Initiative prior to joining the Department of Physics in 2019. She received her BS in physics and mathematics from Brandeis University and her PhD in physics from the University of California at Santa Barbara. Engelhardt is a researcher in the Center for Theoretical Physics and the Black Hole Initiative at Harvard University.

Mark Harnett studies how the biophysical features of individual neurons endow neural circuits with the ability to process information and perform the complex computations that underlie behavior. As part of this work, his lab was the first to describe the physiological properties of human dendrites. He joined the Department of Brain and Cognitive Sciences and the McGovern Institute for Brain Research in 2015. Prior, he was a postdoc at the Howard Hughes Medical Institute’s Janelia Research Campus. He received his BA in biology from Reed College in Portland, Oregon and his PhD in neuroscience from the University of Texas at Austin.

Or Hen investigates quantum chromodynamic effects in the nuclear medium and the interplay between partonic and nucleonic degrees of freedom in nuclei. Specifically, Hen utilizes high-energy scattering of electron, neutrino, photon, proton and ion off atomic nuclei to study short-range correlations: temporal fluctuations of high-density, high-momentum, nucleon clusters in nuclei with important implications for nuclear, particle, atomic, and astrophysics. Hen was an MIT Pappalardo Fellow in the Department of Physics from 2015 to 2017 before joining the faculty in 2017. He received his undergraduate degree in physics and computer engineering from the Hebrew University and earned his PhD in experimental physics at Tel Aviv University.

Sebastian Lourido is interested in learning about the vulnerabilities of parasites in order to develop treatments for infectious diseases and expand our understanding of eukaryotic diversity. His lab studies many important human pathogens, including Toxoplasma gondii, to model features conserved throughout the phylum. Lourido was a Whitehead Fellow at the Whitehead Institute for Biomedical Research until 2017, when he joined the Department of Biology and became a Whitehead Member. He earned his BS from Tulane University in 2004 and his PhD from Washington University in St. Louis in 2012.

Faculty and staff recall Goldman’s unending commitment to his work for more than three decades.

Lillian Eden | Department of Biology

August 7, 2023

Last fall, Stephen “Steve” Goldman passed away at 59 after a courageous battle with amyotrophic lateral sclerosis (ALS). Prior to his passing, Goldman had worked at MIT for more than 30 years, first with Information Systems and Technology, then for the Computational and Systems Biology Initiative, and then in the Department of Biology.

“Steve was an institution,” says Stuart Levine, director of the BioMicro Center in the biology department and Goldman’s supervisor for more than a decade. According to Levine, Goldman was the type of person who had his “whole being” wrapped up in the job: “He did a little bit of everything, and that’s really hard to find these days.”

Steve Goldman was one of the first hires for the fledgling BioMicro Center, according to former supervisor Peter Sorger, whose is now the Otto Krayer Professor of Systems Pharmacology in the Department of Systems Biology at Harvard Medical School. Goldman, Sorger says, was essential for setting up the Department of Biology’s first server-based computing system.

“He brought great enthusiasm and skill to the role, and I also appreciated his sangfroid and sense of humor. This was essential because we were inventing the center’s infrastructure and mission on the fly and were often in the dark — and also down in the steam tunnels. Steve was a real pioneer,” Sorger says.

Before coming to MIT, Goldman lived in New York and worked on Wall Street. He met his wife of 32 years, Brenda Goldman (née Mahar), on a boat in the middle of the Caribbean Sea.

“He came up to me in a white tuxedo and asked me to have dinner,” Brenda Goldman recalls.

They clicked immediately. Around the time of their wedding two years later, Brenda had found a job in Cambridge, Massachusetts, and they were both eager for Steve to find work in the area, far from the high-stress environment of Wall Street.

“I found an ad at MIT and I said, ‘This sounds very much like you,’” Brenda says. After several interviews, he found out he’d gotten a job at MIT the day before their wedding — and the rest, as they say, is history.

Whether it was a weekend or a holiday, if Goldman got an alert that something was wrong, he would always try to follow up, fix the problem, or go in to offer hands-on help, according to Levine.

Brenda even accompanied him a few times, noticing that “there was always somebody around who waved or said hello. We couldn’t get out of the building without seeing someone, no matter which building it was,” she says.

Former department head Alan Grossman recalls many casual conversations about sports, especially baseball and softball.

“He always greeted me with a warm smile and ‘Hello, professor,’” Grossman says. “He truly loved working in our department, and we miss him.”

Goldman’s second love, according to Brenda Goldman, was refereeing sports. Steve would often get to work early so he could wrap up in time to referee or umpire games.

“He had something for almost every season of the year except winter,” Brenda says. “He liked it for the exercise, but he also liked it because it got him off his office chair and interacting with people.”

Steve Goldman was organized — but his workspace was notably less so. It was notorious for being filled with stuff — piles of memory sticks, CDs, cables, and devices open and in various stages of repair. However, Brenda says, “If you told him something broke, he knew what pile of things to pull the magic out of to make it work.”

Levine says Goldman’s death came as a bit of a shock: He had been answering emails just days before his passing.

“He always, always loved working for MIT,” Brenda Goldman says. “He loved computers, and the work gave his life purpose.”

Following his death, the Department of Biology made a contribution in Goldman’s memory to the ALS Association of Massachusetts. In addition to Brenda, his wife of 32 years, Goldman is survived by his children Kevin and Jason Goldman, in-laws, and many nieces and nephews.

August 2, 2023

Greta Friar | Whitehead Institute

August 4, 2023

MIT PhD student Kathrin Kajderowicz is studying how hibernation-like states could pave the way for new hypothermic therapies.

Department of Brain and Cognitive Sciences

August 4, 2023

In 2020, Kathrin “Kat” Kajderowicz’s father passed away from lung cancer. Kajderowicz was in charge of her father’s health care for as long as she can remember. While he suffered from various cardiovascular issues for several years, it wasn’t until the beginning of the Covid-19 pandemic that he was diagnosed with late-stage metastatic small-cell lung cancer. Jumping into a primary caregiver position, she closely monitored the treatments he received from doctors to no avail. “I was frustrated with the many medications he was prescribed without the doctors fully understanding how they interacted with each other,” she says. Even if a single physician had been overseeing his comprehensive treatment plan, she says, they still could not definitively say whether the medication combinations have adverse effects that outweigh any positive impact.

This frustration set her on a scientific journey that has now culminated in her research as a PhD student at MIT’s Department of Brain and Cognitive Sciences (BCS) and the Whitehead Institute for Biomedical Research. “My experience led me to a significant medical problem: How can we eventually shift the medical paradigm to develop treatments that consider not only one specific pathway or problem but contextualize systemic tissue or organ dysfunction?”

To engage with this problem, Kajderowicz studies animals uniquely adapted to handle different stressors and environments, possibly modeling human disease states. “Perhaps we can turn to nature and see how different organisms have adapted to overcome and mitigate similar challenges,” she says.

Kajderowicz now works in Professor Siniša Hrvatin’s lab at Whitehead, where she researches cold tolerance. “I’m interested in exploring the mechanisms underlying cellular cold tolerance in hibernating organisms.” Engineering cold tolerance and stasis has many potential revolutionary future applications. In the near term, her work could improve organ transplantation and cell or tissue preservation. In the longer term, she hopes her work could catalyze a shift in the medical field away from its current crisis-mode approach: “By slowing down bodily processes and disease progression, a lower metabolic state could pave the way for a new class of hypothermic therapies that induce human hibernation-like states for cells, organs, or even whole organisms.”

First-generation student and scientist

Kajderowicz’s clearheaded pursuit of fundamental, large-scale scientific questions has propelled her impressive career as a young scientist. Recently, she was awarded the Paul and Daisy Soros Fellowship for New Americans, recognizing her unique path as the daughter of immigrants from Soviet Poland. Her parents arrived in the United States without having completed higher education degrees, without any savings, knowledge of English, medical insurance, or immigration papers. They worked hard to make a living — her father was a construction worker and her mother a housekeeper — using much of their earnings to become naturalized citizens.

Kajderowicz developed an early interest in a scientific career. “My parents, who didn’t go to college, didn’t push me toward any specific profession,” she says. “This gave me the freedom to explore any field I wanted, and my curiosity naturally led me to science.”

As a teenager, she worked as a golf caddie to help her parents financially. Clients at the golf course assisted her in obtaining internships at biotech and tech companies. Having won Best in Category at the Illinois State Science Fair, Kajderowicz received a substantial scholarship to support her studies at Cornell University, but she continued working to pay for her expenses and tuition. At Cornell, Kajderowicz joined the renowned Lab of Ornithology, where she applied machine-learning techniques to study songbird communication and other behavioral patterns.

Kajderowicz’s journey as a neuroscientist began at Harvard Medical School in Professor Connie Cepko’s lab, where she studied the developmental trajectory of a population of retinal interneurons. “Learning how to identify cell signatures was a fascinating introduction to the complexity of life. But I ultimately realized I wanted to pursue the questions that kept me up at night — both how we process information and how and why these processes change during aging. For me, these are life’s biggest unanswered questions, and I believe neuroscience is the foundation for everything. This led me to MIT’s Department of Brain and Cognitive Sciences.”

Learning from hamsters

Kajderowicz applied and was admitted to over two dozen graduate programs — “but I knew I wanted to go to MIT BCS. That was a no-brainer,” she says. “The department has faculty members in all levels of neuroscience: the cellular and molecular, systems, computational, and cognitive levels. It’s amazing to have all these people under one roof.”

Shortly after starting her graduate work at MIT, Kajderowicz realized she wanted to focus on the cellular level. “I think it’s important first to understand how things work within cells before focusing on function and systems.” She also seeks a translational avenue connecting theory and therapy, bridging the gap between basic science and applied treatment.

Kajderowicz found what she sought at the Whitehead Institute’s Hrvatin Lab and Weissman Lab. “It’s truly unique to have access to two very different communities at MIT. In BCS, I am seen as a biologist, while at the Whitehead Institute, I am more of a neuroscientist. It’s great having folks from different training backgrounds challenging my ideas and work.”

Instead of working directly on how cognition is encoded at the cellular level, Kajderowicz decided to embark on a project that would allow her to figure out how different species survive extreme stressors and environments. She is now developing tools to study cold tolerance across several species on the cellular level.

“Hibernating hamsters can safely endure prolonged durations during which their body temperature drops to 4 degrees [Celsius]. By taking a comparative species approach, I want to identify whether hibernators are uniquely genetically programmed to withstand these conditions or whether non-hibernators don’t activate these genetic pathways,” she says. Next, Kajderowicz hopes to figure out how to transfer or activate cold-protective effects to human cells and, someday, whole humans. While she isn’t directly studying the root of cognition, she hopes her research will help maintain or enhance cognitive functioning throughout aging by pushing the boundaries of the types of medicines and therapeutics available.

Building a scientific community

Kajderowicz’s involvement in the scientific community extends beyond her immediate work. At the height of the pandemic, she initiated a digital platform facilitating conversations on biotechnology trends among researchers, biotech professionals, venture capitalists, and others interested in staying updated on cutting-edge developments. Known as “DNA Deviants,” the community she built consists of several thousand active members on several social media platforms.

“It started with an informal journal club I had with some friends, where we would meet over coffee and discuss new papers. Then, when the pandemic shut down everything, I started a real-time podcast on the Clubhouse app with a friend, discussing emerging biotech trends. Eventually, it became an online journal club, and people just kept joining. We got experts to serendipitously join conversations within their realm of expertise from around the world.” Today, almost a dozen PhD, MD-PhD, and motivated undergraduates worldwide take turns leading conversations with different paper authors.

“It’s been incredibly rewarding to remain connected not only to my work, but also to gain a comprehensive understanding of what’s happening in the world,” Kajderowicz says. “You always need to look beyond your immediate circle.”