This facility provides access to instrumentation for in vivo, whole animal imaging, including bioluminescence, microCT, PET/CT, ultrasound and small animal MRI technologies. The work here supports translational efforts through the use of refined mouse models of human cancers in preclinical testing of biosensors for tumor detection and monitoring, diagnostic assays, cancer vaccines, drug delivery systems and tumor-targeting modalities, and chemotherapeutic response and drug resistance.