Education
- PhD, 1974, SUNY Albany
Research Summary
Our goal is to understand the ecology and evolution of ocean microbes and how they influence global biogeochemical cycles. We focus on the cyanobacterium Prochlorococcus, which is the smallest and most abundant microbe in ocean ecosystems — sometimes accounting for half the total photosynthetic biomass. We use this model system to study life across all scales — from the genome to the ecosystem.Awards
- Crafoord Prize, 2019
- Generalitat of Catalonia, Ramon Margalef Prize in Ecology, 2013
- American Association for the Advancement of Science, Fellow, 2012
- National Medal of Science, 2011
- National Academy of Sciences, Alexander Agassiz Medal, 2010
- National Academy of Sciences, Member, 2003
- John Simon Guggenheim Memorial Foundation, Guggenheim Fellowship, 1997
- American Academy of Arts and Sciences, Fellow, 1992
Key Publications
- Metabolic evolution and the self-organization of ecosystems. Braakman, R, Follows, MJ, Chisholm, SW. 2017. Proc Natl Acad Sci U S A 114, E3091-E3100.
doi: 10.1073/pnas.1619573114PMID:28348231 - Prochlorococcus: the structure and function of collective diversity. Biller, SJ, Berube, PM, Lindell, D, Chisholm, SW. 2015. Nat Rev Microbiol 13, 13-27.
doi: 10.1038/nrmicro3378PMID:25435307 - Single-cell genomics reveals hundreds of coexisting subpopulations in wild Prochlorococcus. Kashtan, N, Roggensack, SE, Rodrigue, S, Thompson, JW, Biller, SJ, Coe, A, Ding, H, Marttinen, P, Malmstrom, RR, Stocker, R et al.. 2014. Science 344, 416-20.
doi: 10.1126/science.1248575PMID:24763590 - Bacterial vesicles in marine ecosystems. Biller, SJ, Schubotz, F, Roggensack, SE, Thompson, AW, Summons, RE, Chisholm, SW. 2014. Science 343, 183-6.
doi: 10.1126/science.1243457PMID:24408433
Recent Publications
- Novel integrative elements and genomic plasticity in ocean ecosystems. Hackl, T, Laurenceau, R, Ankenbrand, MJ, Bliem, C, Cariani, Z, Thomas, E, Dooley, KD, Arellano, AA, Hogle, SL, Berube, P et al.. 2023. Cell 186, 47-62.e16.
doi: 10.1016/j.cell.2022.12.006PMID:36608657 - Filter Plating Method for Rendering Picocyanobacteria Cultures Free of Heterotrophic Bacterial Contaminants and Clonal. Kearney, SM, Coe, A, Castro, KG, Chisholm, SW. 2022. Front Microbiol 13, 821803.
doi: 10.3389/fmicb.2022.821803PMID:35250937 - Siderophores as an iron source for picocyanobacteria in deep chlorophyll maximum layers of the oligotrophic ocean. Hogle, SL, Hackl, T, Bundy, RM, Park, J, Satinsky, B, Hiltunen, T, Biller, S, Berube, PM, Chisholm, SW. 2022. ISME J 16, 1636-1646.
doi: 10.1038/s41396-022-01215-wPMID:35241788 - Prochlorococcus extracellular vesicles: molecular composition and adsorption to diverse microbes. Biller, SJ, Lundeen, RA, Hmelo, LR, Becker, KW, Arellano, AA, Dooley, K, Heal, KR, Carlson, LT, Van Mooy, BAS, Ingalls, AE et al.. 2022. Environ Microbiol 24, 420-435.
doi: 10.1111/1462-2920.15834PMID:34766712 - Coping with darkness: The adaptive response of marine picocyanobacteria to repeated light energy deprivation. Coe, A, Biller, SJ, Thomas, E, Boulias, K, Bliem, C, Arellano, A, Dooley, K, Rasmussen, AN, LeGault, K, O'Keefe, TJ et al.. 2021. Limnol Oceanogr 66, 3300-3312.
doi: 10.1002/lno.11880PMID:34690365 - Microbial diversity of co-occurring heterotrophs in cultures of marine picocyanobacteria. Kearney, SM, Thomas, E, Coe, A, Chisholm, SW. 2021. Environ Microbiome 16, 1.
doi: 10.1186/s40793-020-00370-xPMID:33902739 - Toward a genetic system in the marine cyanobacterium Prochlorococcus. Laurenceau, R, Bliem, C, Osburne, MS, Becker, JW, Biller, SJ, Cubillos-Ruiz, A, Chisholm, SW. 2020. Access Microbiol 2, acmi000107.
doi: 10.1099/acmi.0.000107PMID:33005871 - Frequency of mispackaging of Prochlorococcus DNA by cyanophage. Laurenceau, R, Raho, N, Forget, M, Arellano, AA, Chisholm, SW. 2021. ISME J 15, 129-140.
doi: 10.1038/s41396-020-00766-0PMID:32929209 - Publisher Correction: Marine microbial metagenomes sampled across space and time. Biller, SJ, Berube, PM, Dooley, K, Williams, M, Satinsky, BM, Hackl, T, Hogle, SL, Coe, A, Bergauer, K, Bouman, HA et al.. 2019. Sci Data 6, 47.
doi: 10.1038/s41597-019-0054-1PMID:31113983 - Co-culture and biogeography of Prochlorococcus and SAR11. Becker, JW, Hogle, SL, Rosendo, K, Chisholm, SW. 2019. ISME J 13, 1506-1519.
doi: 10.1038/s41396-019-0365-4PMID:30742057
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