Education
- PhD, 1971, MIT
- MA, 1970, Biochemistry, Cambridge University
- BA, 1966, Biochemistry, Cambridge University
Research Summary
We study the mechanisms underlying the spread of tumor cells throughout the body, known as metastasis. We are particularly interested in the role of the extracellular matrix — a fibrillar meshwork of proteins that surrounds both normal and tumor cells, which plays many important roles in tumor progression. We also investigate changes in the metastatic cells themselves and in the contributions of normal cells, both in terms of metastasis and other bodily functions.
Awards
- Paget-Ewing Award, Metastasis Research Society, 2018
- Inaugural American Society for Cell Biology (ASCB) Fellow, 2016
- American Association for Cancer Research (AACR) Academy, Fellow, 2014
- Distinguished Investigator Award, International Society for Matrix Biology, 2012
- Earl Benditt Award, North American Vascular Biology Organization, 2010
- Robert and Claire Pasarow Medical Research Award – Cardiovascular, 2008
- E.B. Wilson Medal, American Society for Cell Biology, 2007
- President, American Society for Cell Biology, 2000
- Gairdner Foundation International Award, 1997
- National Academy of Sciences, Member, 1996
- National Academy of Medicine, Member, 1995
- Royal Society of London, Fellow, 1989
- Howard Hughes Medical Institute, HHMI Investigator, 1988
- American Association for the Advancement of Science, Fellow, 1987
- American Academy of Arts and Sciences, Fellow, 1987
- John Simon Guggenheim Memorial Foundation, Guggenheim Fellowship, 1982
Media Inquiries
For media inquiries, please email
rhynes-admin@mit.edu.
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