Leona Samson

Leona Samson

Uncas and Helen Whitaker Professor Emeritus; American Cancer Society Research Professor Emeritus

Leona Samson analyzes toxic chemicals frequently used in cancer chemotherapy to prevent further DNA damage.



Lindsay King



Assistant Phone


PhD, University College London

Research Summary

Leona Samson studies alkylating agents, which are toxic chemicals used in chemotherapy that can damage DNA. To do so, she probes the large number of responsive genes that protect cells against alkylation toxicity. She also dissects the molecular mechanisms by which alkylating agents signal these very important downstream events. Leona Samson is no longer accepting students.


  • American Association for the Advancement of Science, Fellow, 2007
  • National Academy of Medicine, Member, 2003
  • American Cancer Society Research Professor, 2001-2011
  • Radcliffe Fellow, 2013-2014
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Photo credit: Ed Quinn