
Genetically Engineered Models (GEM) Core Facility
Whitehead Institute, Room 461
Contact: Styliani (Stella) Markoulaki
This facility generates genetically modified mice, using traditional and CRISPR/Cas9 techniques to understand gene function and model human disease. Even though the traditional way is complex, costly and time-consuming, it is still used to achieve difficult mutations. CRISPR in mouse embryos can generate mutations in multiple genes and achieve deletions or insertions in as little as four weeks. Regardless of the method, the facility is here to generate any mouse model in the fastest and most cost-efficient manner.