This facility integrates the various research goals of members of the Picower and McGovern Institutes, as well as the Department of Brain and Cognitive Sciences, to create human and animal cell models of diseases. The iPS Core Facility has produced over 60 patient-specific iPS cells from Schizophrenia, Bipolar disease, Depression, Rett syndrome, Alzheimer disease, Down Syndrome, and healthy person’s skin fibroblasts as controls.