Theresa Wasylenko

Theresa Wasylenko

Technical Instructor

Theresa Wasylenko works with department faculty to teach and provide instructional support for Biology undergraduate lecture and lab courses.

617-253-3819

Phone

68-074C

Office

Theresa received a PhD in human genetics at MIT Biology in the lab of David Housman. She focused specifically on the pathogenesis of Huntington's disease and other neurodegenerative disorders, applying next generation sequencing analyses to better understand molecular disease mechanisms. Theresa served as a lecturer at Olin College of Engineering before returning to MIT Biology as a technical instructor in 2018.

She collaborates with faculty, fellow instructors, and teaching assistants to develop and teach introductory biology lab courses. She is currently involved in a new course, 7.002. This shortened lab course emphasizes fundamental techniques and approaches used in biological research, while introducing students to the diverse research programs at MIT. At the same time, she instructs 7.02, a traditional biology lab that focuses on scientific communication. She is usually around the teaching lab in the basement of Building 68 — come visit if you have questions or thoughts about our lab courses!

Key Publications

  1. Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. Nath, SR, Yu, Z, Gipson, TA, Marsh, GB, Yoshidome, E, Robins, DM, Todi, SV, Housman, DE, Lieberman, AP. 2018. J. Clin. Invest. 128, 3630-3641.
    doi: 10.1172/JCI99042PMID:29809168
  2. HSF1-dependent and -independent regulation of the mammalian in vivo heat shock response and its impairment in Huntington's disease mouse models. Neueder, A, Gipson, TA, Batterton, S, Lazell, HJ, Farshim, PP, Paganetti, P, Housman, DE, Bates, GP. 2017. Sci Rep 7, 12556.
    doi: 10.1038/s41598-017-12897-0PMID:28970536
  3. Aberrantly spliced HTT, a new player in Huntington's disease pathogenesis. Gipson, TA, Neueder, A, Wexler, NS, Bates, GP, Housman, D. 2013. RNA Biol 10, 1647-52.
    doi: 10.4161/rna.26706PMID:24256709
  4. Targeting H3K4 trimethylation in Huntington disease. Vashishtha, M, Ng, CW, Yildirim, F, Gipson, TA, Kratter, IH, Bodai, L, Song, W, Lau, A, Labadorf, A, Vogel-Ciernia, A et al.. 2013. Proc. Natl. Acad. Sci. U.S.A. 110, E3027-36.
    doi: 10.1073/pnas.1311323110PMID:23872847
  5. Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease. Sathasivam, K, Neueder, A, Gipson, TA, Landles, C, Benjamin, AC, Bondulich, MK, Smith, DL, Faull, RL, Roos, RA, Howland, D et al.. 2013. Proc. Natl. Acad. Sci. U.S.A. 110, 2366-70.
    doi: 10.1073/pnas.1221891110PMID:23341618